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Over 70% of Chinese Viewers Paid for Subscriptions to Stream Series Online in the First Half of 2020

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BEIJING, July 31, 2020 /PRNewswire/ — Maoyan Entertainment (“Maoyan” or “the Company”) (Hong Kong: 1896), a leading platform providing innovative Internet-empowered entertainment services in China, released a report on China’s TV and web series market for the first half of 2020. The report shows that during the COVID-19 pandemic, about 74% of respondents paid for platform subscriptions to stream series online, as consumers shifted from offline to online entertainment consumption.

The report examines the TV and web series market landscape, audience entertainment behavior, as well as TV and web series distribution and promotion channels in the first half of 2020. The report is based on a Maoyan Research Institute market survey conducted at the beginning of July and on market data from entertainment data analysis platform Maoyan Zhiduoxing and other sources.

Market highlights:

  • The TV and web series market gained viewership as people remained at home during the first half of 2020.
  • About 69% of respondents spent more time watching TV and web series in the first half of 2020 than they had in the same period last year. On average, viewers watched five TV and web series over the first half of 2020.
  • Viewers have acclimated to paying for online content. About 74% of respondents said they paid for subscriptions to watch series online during the period.
  • Streaming platform releases grew in the first half of 2020. A total of 137 web series were released in the first half, an increase of 26.9% from 108 titles in the first half of 2019.
  • Long-form video platforms (iQIYI, Tencent Video and Youku) and short-form video platforms (TikTok and Kuaishou) were the main channels for series distribution and promotion.

TV and web series gained viewership

While the movie industry was severely hit by the COVID-19 pandemic, the TV and web series market gained viewership as consumers remained at home in the first half of 2020. A total of 190 TV and web series were released in the first half of 2020, including 53 TV series and 137 web series. According to the report, the overall popularity of new releases in the first half of 2020 was significantly higher than those released in the first half of 2019.


Number of new TV series

Number of new web series

H1 2019

73

108

H1 2020

53

137

According to the report, about 69% of respondents spent more time watching TV and web series in the first half of 2020 than they had in the same period last year. On average, viewers watched five TV and web series during the first half of 2020.

Time spent watching series in H1 2020 compared to H1 2019

Percentage of respondents

Significant increase

33%

Slight increase

36%

About the same

18%

Slight decline

10%

Significant decline

3%

Platforms offer both membership subscriptions to access the library of TV and web series, as well as individual purchase options for specific series. According to the report, about 74% of respondents said they paid for a membership subscription, while about 32% of respondents reported having made single payments to watch a series on a platform. When asked about their preferred spending, about 94% of respondents preferred spending RMB30 or less on a single show. These responses signal that viewers have acclimated to paying for online content, a spur for the industry to create more high-quality content.

Paid for platform membership subscription

Percentage of total respondents

Yes

74%

Don’t remember

5%

No

21%

Made single purchases to watch a series online

Percentage of total respondents

Yes

32%

Don’t remember

10%

No

59%

Preferred spending on a single show (RMB)

Percentage of total respondents

Less than 5

42%

From 6 to 10

26%

From 11 to 20

17%

From 21 to 30

9%

From 31 to 40

0%

From 41 to 50

2%

More than 51

5%

Long-form video platforms (iQIYI, Tencent Video and Youku) and short-form video platforms (TikTok and Kuaishou) were the main sources for TV and web series news and information, followed by WeChat Moments, WeChat official accounts and Weibo.

Sources for series news and information

Percentage of total respondents

Long-form video platforms (iQIYI, Tencent Video and Youku)

64%

Short-form video platforms (TikTok and Kuaishou)

43%

WeChat Moments/WeChat official accounts

40%

Weibo

35%

Online ticketing platforms (Maoyan and Taopiaopiao)

34%

Friends/family members discussion

28%

Movie and TV news and information platforms (Douban,
Zhihu)

26%

News and information platforms (Toutiao, The Paper and
36Kr)

14%

Online communities (Baidu Tieba and Hupu)

10%

Music entertainment platforms

9%

Newspapers and Magazines

7%

Advertisements on subway and bus stations

7%

Others

1%

(Respondents were instructed to select all options that apply)

According to the report, suspense and crime, teen, comedy, sci-fi and costume and historical dramas were among the most popular genres of TV and web series in the first half of 2020.

Most popular TV and web series genres in H1 2020

Percentage of respondents

Suspense and crime

55%

Teen

49%

Comedy

49%

Sci-fi

44%

Costume and historical dramas

40%

(Respondents were instructed to select all options that apply)

According to the survey, the top five most important factors respondents consider when selecting a series are good reputation and a high rating score (63%), favorite genres (56%), favorite actors/directors (43%), popularity/high viewing volume (40%) and a good series synopsis (39%).

Factors considered when choosing a series

Percentage of total respondents

Good reputation and a high rating score

63%

Favorite genres

56%

Favorite actors/directors

43%

Popularity/high viewing volume

40%

Good series synopsis

39%

Friends/family members recommendations

30%

Attracted by clips of the show posted on short-video
platforms or Weibo

30%

Trailers/a special collection of short videos

28%

Adapted from my favorite IP content

21%

Catchy title

19%

KOLs/WeChat official accounts recommendations

17%

Broadcast/release time

16%

Catchy show poster

11%

Prominent placement on the streaming platform

7%

Random choice

6%

Others

0%

(Respondents were instructed to select all options that apply)

About 86% of respondents usually watch TV and web series alone. When asked about their primary reason for watching TV and web series, about 84% of respondents said for relaxation and entertainment, followed by to kill time (62%), to watch a favorite celebrity (41%), to gain knowledge (30%), and to feel accompanied (26%).

With whom do you usually watch TV and web series?

Percentage of total respondents

By myself

86%

Spouse

20%

Friends/colleagues/classmates

16%

Parents

15%

Boyfriend/Girlfriend

12%

Other family members

6%

Children

5%

(Respondents were instructed to select all options that apply)

Reasons for watching TV and web series

Percentage of total respondents

For relaxation and entertainment

84%

Kill time

62%

Watch favorite celebrities

41%

Gain knowledge

30%

Feel accompanied

26%

Others

1%

(Respondents were instructed to select all options that apply)

Since online platforms offer adjusted playback speeds, a segment of viewers watch TV and web series at twice the normal speed or above. Survey results show that 32% of respondents watched series at twice the normal playback speed or faster, while 24% fast forward or skip while watching and 15% did not finish a complete series.

According to the survey, about 80% of respondents said they often or sometimes feel unsatisfied with a TV or web series. When asked the main reasons for not enjoying it, about 67% said that they were not interested in the series genre, while 54% said that the series content quality did not meet their expectations.  

Reasons for feeling unsatisfied with a TV or web series

Percentage of total respondents

Not interested in the genre

67%

Content quality did not meet the expectation

54%

Series is slow to add new episodes

40%

Doesn’t feature favorite actors or celebrities in the
current series

23%

(Respondents were instructed to select all options that apply)

Streaming platforms flourish in the first half of 2020

The Online streaming of series has grown rapidly in the first half of 2020. A total of 137 web series released in the first half of 2020, increased by 26.9% from 108 titles in the first half of 2019. Among the newly released series in the first half of 2020, about 31% of those available to stream online were released on iQIYI, about 24% were released on Youku, about 22% were released on Tencent Video and about 12% on Mango TV.

Platform

Percentage of total new series in H1 2020 available online

iQIYI

31%

Youku

24%

Tencent Video

22%

Mango TV

12%

Others

11%

According to the report, Tencent Video released 24 new titles on the platform exclusively, generating an average of 8,377 Maoyan Overall Trend index, which was higher than other streaming platforms.

Maoyan Overall Trend index is an index that analyzes the popularity of movies and series. It is a multi-dimensional indicator collecting and calculating playback data in real-time from China’s seven leading streaming platforms, including Tencent Video, iQIYI, Youku, Mango TV, TV.Sohu, LETV and PPTV, as well as combining data from social media platforms and analyzing the amount of attention that media gives to related stories. The resulting numbers do not have a scaled range and keeps updating in real-time. The higher the index, the more popular the title is in the current market.


Number of new series released
exclusively on each platform

Average Maoyan Overall Trend
index

Tencent Video

24

8,377

iQIYI

54

8,353

Mango TV

15

8,296

Youku

36

7,924

Among the top 10 series with the historical highest Maoyan Overall Trend index, four titles were streamed exclusively on the iQIYI platform, three were on Tencent Video platform, and one title was solely streamed on Youku platform.

Top 10 new released series

The historical peak of
Maoyan Overall Trend index

Streaming platform

Winter Begonia

9,941

iQIYI

Candle in the Tomb: The Lost Caverns

9,887

Tencent Video

Three Lives Three Worlds

9,866

Tencent Video

The Love Lasts Two Minds

9,854

iQIYI

Ipartment Season 5

9,849

iQIYI

Held in the Lonely Castle

9,828

Tencent Video

Love a Lifetime

9,828

iQIYI and Youku

Love Advanced Customization

9,816

iQIYI, Tencent Video and
Youku

Love Is All

9,797

Youku

The Bad Kids

9,797

iQIYI

While web series were popular in the first half of 2020, the performance of TV series was not as strong. The Urban TV drama “I Will Find You a Better Home,” which aired on Beijing Satellite TV and Dragon Satellite TV, was the only title with a TV rating exceeding 2% in the first half of 2020.

For distribution and promotion of TV and web series, long-form video platforms (iQIYI, Tencent Video and Youku) and short-form video platforms (TikTok and Kuaishou) were the two main channels to promote shows and attract the respondents. Short-form video platforms experienced an enormous surge in the first half of 2020 and became one of the most important media matrices for promotion and distribution. Clips from TV and web series were often re-created, published and distributed by users on short-form video platforms, receiving hundreds of thousands of likes and comments.

With the resumption of China’s entertainment industry, Maoyan will continue leveraging our own cutting-edge big data capabilities and advantages to explore the market’s growth potential further.

About Maoyan Entertainment

Maoyan Entertainment (Hong Kong: 1896) is a leading platform providing innovative Internet-empowered entertainment services in China. Since its inception, Maoyan has grown from an online movie ticketing service provider to an innovative one-stop platform for entertainment services. Maoyan has a comprehensive strategy to become a leading platform servicing the entire entertainment industry in China. The upgraded strategy is supported by five key platform pillars: comprehensive entertainment ticketing platform, products platform, data platform, marketing platform, and financing platform.

For media inquiries, please contact:

Edmond Lococo
ICR Inc.
Email: [email protected]
Tel: +86 138-1079-1408

SOURCE Maoyan Entertainment

Related Links

www.maoyan.com

This story has been sourced from a third party syndicated feed, agencies. News Galiyara accepts no responsibility or liability for its dependability, trustworthiness, reliability, and data of the text. DigitalGaliyara (OPC) Private Limited management reserves the sole right to alter, delete or remove (without notice). If you have any concerns with the Content, then please write to us at the mail@digitalgaliyara.com Source – PRNewsWire

Press Release

Qingdao Conson Hosts Urban Economy High-Quality Development Forum and Hai Tian Center Launch Ceremony to Accelerate the City's Growth

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UEFA EURO 2020 Sponsor Hisense Showcases Hisense U7 TV at the Tournament

QINGDAO, China, June 21, 2021 /PRNewswire/ — Themed “Building and Sharing a Win-Win Future”, the Urban Economy High-Quality Development Forum & Hai Tian Center Launch Ceremony was hosted by Qingdao Conson Development (Group) at Hai Tian Center in Qingdao on June 20.

 

Qingdao Conson Hosts Urban Economy High-Quality Development Forum and Hai Tian Center Launch Ceremony to Accelerate the City's Growth

With a height of 369 meters (1210.63 ft), Hai Tian Center is home to super-grade A offices, the five-star Haitian Hotel, the St. Regis Qingdao, the Cloud Art Center, an observation deck, the Cloud Diamond Club, the Haitian Mall and Haitian Mansion. As a new landmark, Hai Tian Center will serve as a state-of-the-art locale and venue of choice for meetings and conferences that enhance the city’s service capabilities and influences how the city evolves.

“Conson Group will fully deploy the potential value of Hai Tian Center in attracting investment, stimulating domestic demand, upgrading consumption, and developing a headquarters economy. The Center provides access to a high-quality living space and lifestyle experience for the local populace while becoming a new force to further enhance the vitality, lead next-stage development and redefine the personality of the city of Qingdao,” said Wang Jianhui, Secretary of Party Committee and Chairman of Qingdao Conson Development (Group).

He views the Hai Tian Center as a culmination of all the city has aspired to, a meaningful addition to the city’s legacy and venue par excellence for important meetings and events, while driving the transformation of Qingdao into an open, modern, dynamic and fashionable international metropolis.

Government leaders and officials of Qingdao present at the event commented that, major projects such as Hai Tian Center are breakthrough events that speed up the transition from old to new economic engines. The trouble-free construction and smooth operation of the center bodes well for it to serve as a facilitator of the city’s high-quality economic and social development while enhancing the region’s overall competitiveness.

Long Yongtu, former vice minister of China’s Ministry of Foreign Trade and Economic Cooperation and co-chairman of the Sino-International Entrepreneurs Federation (SIEF), noted: “China is accelerating the construction of a new development pattern with domestic circulation as the mainstay along with the mutual promotion of dual circulation. Against this backdrop, quality and openness are the key to urban economic development.” He spoke highly of Qingdao’s active role in promoting the high-quality development of the city driven by the super-high-rise urban complex such as Hai Tian Center. “I hope that Hai Tian Center can be developed into a center for talents, the service economy, and investments, which can assist Qingdao in its transformation into an open, modern and dynamic international metropolis.”

Looking ahead, Hai Tian Center plans to integrate its competitive resources to facilitate collaboration among businesses and organizations in and around Qingdao with the goal of establishing a modern business ecosystem encompassing information service providers, manufacturers, financial service providers, training and educational institutions and technology firms.

Media contact:

Mr. Gu

+86-158-5328-5676

Video – https://mma.prnewswire.com/media/1537511/6_21_30s_Video.mp4

Photo – https://mma.prnewswire.com/media/1537499/Image1.jpg 

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Press Release

The Pressing Need for Early Detection of Mucormycosis during COVID-19

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Fapon Biotech calls for cooperation with academic and industry partners in developing mucormycosis diagnostic tests to ease the challenge by sharing the abilities of upstream raw material development platforms and downstream reagent application platforms.

DONGGUAN, China, June 21, 2021 /PRNewswire/ — Mucormycosis or black fungus, a devastating infection that soars in India during COVID-19 has seized global attention. Recently, the country’s mucormycosis cases reached over 57,150 and resulted in 54% mortality. Apart from the association with high diabetes prevalence in India, COVID-19 infected countries (Pakistan, Russia, Nepal, Chile, Brazil, etc.) have also described the same issue, areas with high diabetes and COVID-19 infection rates should be alarmed.

Fapon Biotech calls for cooperation with academic and industry partners in developing mucormycosis diagnostic tests to ease the challenge by sharing the abilities of upstream raw material development platforms and downstream reagent application platforms.

Unfortunately, mucormycosis is always being diagnosed late with prolonged COVID-19 healthcare burdens that deteriorate the situation. As a company making continuous research and contribution to the world’s major infectious diseases with the mission to Enable Disease Identification Earlier, More Accurate, Convenient and Affordable, Fapon Biotech Inc. (Fapon Biotech) calls for cooperation with academic and industry partners in developing mucormycosis diagnostic tests to ease the challenge by sharing the abilities of upstream raw material development platforms and downstream reagent application platforms.

Fapon Biotech is one of the mainstream COVID-19 reagent raw material suppliers with proven experiences helping partners to launch accredited COVID-19 reagents in a short time. The company has over 1000 IVD partners worldwide with more than 10 years of business operation in India. Its technology platforms can match the R&D process from partners easily and provide supports from biomarker discovery to commercialization. Through different application platforms of Fapon Biotech (Colloidal Gold/Immunofluorescence/ELISA/CLIA/Latex-Enhanced Immunoturbidimetry/PCR/etc.), biomarkers can quickly complete the process of application development. For partners encountering production challenges, OEM and contract manufacturing services with the capacity reaching hundreds of grams of each batch are available. Because of a strong relationship with laboratories and IVD manufacturers in India, cooperating with Fapon Biotech will have the access to more resources and commercial opportunities, such as clinical samples for research and product validation, technology iterations, product launch and promotion, etc.

As the virus continues its mutation and triggers diseases like mucormycosis to complicate the situation, rapid responses via global cooperation will be crucial for areas with overwhelmed healthcare burdens. Fapon Biotech is committed to fueling the advancement of COVID-19 diagnosis through collaborations with international IVD partners.

About Fapon Biotech

Fapon Biotech was founded in 2001. Guided by the mission of “Enable Disease Identification Earlier, More Accurate, Convenient and Affordable,” the company focuses on the future needs of biotechnology developments and provides global diagnostic companies with high-performance IVD reagent raw materials, such as antigens, antibodies, and enzymes, as well as one-stop solutions with instrument and reagent services.

Photo – https://mma.prnewswire.com/media/1537054/Fapon_Biotech.jpg

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Press Release

RedHill Biopharma Announces Presentation of Positive Oral Opaganib Phase 2 Data in COVID-19

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RedHill Biopharma logo

Positive U.S. Phase 2 safety and efficacy data for opaganib, a leading novel, oral, dual-mechanism drug candidate for moderate-to-severe COVID-19, presented at the World Microbe Forum

Opaganib was associated with a reduction in the need for supplemental oxygen support, earlier time to discharge from hospital and was well tolerated

Opaganib’s global 475-patient Phase 2/3 study is fully enrolled, with study completion expected in the coming weeks

Opaganib is host-targeted and expected to be effective against emerging viral variants

TEL AVIV, Israel and RALEIGH, NC, June 21, 2021 /PRNewswire/ — RedHill Biopharma Ltd. (Nasdaq: RDHL) (“RedHill” or the “Company”), a specialty biopharmaceutical company, today announced presentation of the positive Phase 2 safety and efficacy data for oral opaganib (Yeliva®, ABC294640)[1] in hospitalized patients with COVID-19 pneumonia at the World Microbe Forum (WMF) 2021 (poster #: 5574).

RedHill Biopharma logo

Results and post hoc analyses of data from the 40-patient U.S. Phase 2 study were presented in a poster entitled, “Opaganib, an Oral Sphingosine Kinase-2 (SK2) Inhibitor in COVID-19 Pneumonia: A Randomized, Double-blind, Placebo-controlled Phase 2A Study, in Adult Subjects Hospitalized with SARS-CoV-2 Positive Pneumonia (NCT: 04414618)“[2]. Patients in the study were randomized to receive either opaganib or placebo in addition to standard of care (SoC), predominantly including dexamethasone and/or remdesivir. Findings include:

  • 50% of patients treated with opaganib (n=22) reached room air by Day 14 compared to 22% in the placebo group (n=18). The benefit of reaching room air by Day 14 for patients on opaganib was maintained regardless of whether the patients were receiving dexamethasone and/or remdesivir
  • 86.4% of patients treated with opaganib were discharged from hospital by Day 14 compared to 55.6% of patients treated with placebo
  • Median time to discharge was 6 days for the opaganib group compared to 7.5 days for the placebo group
  • 81.8% of opaganib patients achieved a 2-point improvement in the WHO Ordinal Scale compared to 55.6% of patients in the placebo group – achieved in a median time of 6 days versus 7.5 days, respectively
  • No significant differences in safety-related measures between the two groups (with diarrhea being the main treatment-emergent difference in tolerability)

“The need for an effective oral therapy to treat COVID-19 is clear. Such a therapy would greatly improve our ability to manage this pandemic,” said Kevin Winthrop, MD, MPH, Professor of Infectious Diseases at Oregon Health & Science University, who presented the findings at WMF. “These data, from this proof-of-concept clinical study of opaganib in patients with severe COVID-19, suggest a potential role of SK2 inhibition in combating the effects of this virus. With much more data on opaganib expected in the coming weeks, we could make some real progress toward having access to a much-needed oral therapy for patients who currently have a paucity of options available to them.”

“Presentation of these positive data from our exploratory Phase 2 study support our growing confidence that opaganib could be the first novel, oral therapy to demonstrate efficacy in the treatment of COVID-19 in a large late-stage study. With the recent completion of enrollment of our 475-patient global Phase 2/3 study, we will have a clearer picture of that in the very near future,” said Mark L. Levitt, MD, Ph.D., Medical Director at RedHill. “Opaganib acts on both the cause and effect of COVID-19 via a unique dual antiviral and anti-inflammatory mode of action. Being host-targeted, opaganib is also expected to maintain effect against the emerging SARS-CoV-2 variants, which continue to threaten the progress being made against the pandemic and underscore the urgent need for effective COVID-19 therapeutics.”

The global 475-patient Phase 2/3 study of opaganib in severe COVID-19 has been approved in 10 countries and completed enrollment, through 57 participating sites, on June 6th. The primary endpoint of the study is the proportion of patients breathing room air without oxygen support by Day 14. Additional important outcome measures, such as time to discharge from hospital, improvement according to the World Health Organization Ordinal Scale for Clinical Improvement and incidence of intubation and mortality, will also be captured in the follow-up period of up to 6 weeks. The study received four independent DSMB recommendations to continue following unblinded safety reviews and a futility review. Additionally, an evaluation of the blinded blended intubation and mortality rates to date was encouraging as compared to reported rates of mortality from large platform studies such as RECOVERY, and other studies in similar patient populations[3].

About Opaganib (Yeliva®, ABC294640)

Opaganib, a new chemical entity, is a proprietary, first-in-class, orally-administered, sphingosine kinase-2 (SK2) selective inhibitor, with dual anti-inflammatory and antiviral activity, that is host-targeted and is therefore expected to be effective against emerging viral variants. Opaganib has also shown anticancer activity and has the potential to target multiple oncology, viral, inflammatory, and gastrointestinal indications.

Opaganib is being evaluated as a treatment for COVID-19 pneumonia in a global Phase 2/3 study, which recently completed enrollment, and has demonstrated positive safety and efficacy signals in preliminary top-line data from the 40-patient U.S. Phase 2 study.

Opaganib has also received Orphan Drug designation from the U.S. FDA for the treatment of cholangiocarcinoma and is being evaluated in a Phase 2a study in advanced cholangiocarcinoma and in a Phase 2 study in prostate cancer.

Opaganib demonstrated potent antiviral activity against SARS-CoV-2, the virus that causes COVID-19, completely inhibiting viral replication in an in vitro model of human lung bronchial tissue. Additionally, preclinical in vivo studies have demonstrated opaganib’s potential to ameliorate inflammatory lung disorders, such as pneumonia, and has shown decreased fatality rates from influenza virus infection and ameliorated Pseudomonas aeruginosa-induced lung injury by reducing the levels of IL-6 and TNF-alpha in bronchoalveolar lavage fluids[4].

The ongoing studies with opaganib are registered on www.ClinicalTrials.gov, a web-based service by the U.S. National Institute of Health, which provides public access to information on publicly and privately supported clinical studies.   

About RedHill Biopharma    

RedHill Biopharma Ltd. (Nasdaq: RDHL) is a specialty biopharmaceutical company primarily focused on gastrointestinal and infectious diseases. RedHill promotes the gastrointestinal drugs, Movantik® for opioid-induced constipation in adults[5], Talicia® for the treatment of Helicobacter pylori (H. pylori) infection in adults[6], and Aemcolo® for the treatment of travelers’ diarrhea in adults[7]. RedHill’s key clinical late-stage development programs include: (i) RHB-204, with an ongoing Phase 3 study for pulmonary nontuberculous mycobacteria (NTM) disease; (ii) opaganib (Yeliva®, ABC294640), a firstinclass SK2 selective inhibitor targeting multiple indications with positive Phase 2 COVID-19 data and an ongoing Phase 2/3 program for COVID-19 and Phase 2 studies for prostate cancer and cholangiocarcinoma ongoing; (iii) RHB-107 (upamostat), a serine protease inhibitor in a U.S. Phase 2/3 study as treatment for symptomatic COVID-19, and targeting multiple other cancer and inflammatory gastrointestinal diseases; (iv) RHB-104, with positive results from a first Phase 3 study for Crohn’s disease; (v) RHB-102 (Bekinda®), with positive results from a Phase 3 study for acute gastroenteritis and gastritis and positive results from a Phase 2 study for IBS-D; and (vi) RHB106, an encapsulated bowel preparation. More information about the Company is available at www.redhillbio.com / https://twitter.com/RedHillBio.         

This press release contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995. Such statements may be preceded by the words “intends,” “may,” “will,” “plans,” “expects,” “anticipates,” “projects,” “predicts,” “estimates,” “aims,” “believes,” “hopes,” “potential” or similar words. Forward-looking statements are based on certain assumptions and are subject to various known and unknown risks and uncertainties, many of which are beyond the Company’s control and cannot be predicted or quantified, and consequently, actual results may differ materially from those expressed or implied by such forward-looking statements. Such risks and uncertainties include the delay in last patient visit and top-line data from the Phase 2/3 COVID-19 study for opaganib, that the Phase 2/3 COVID-19 study for opaganib may not be successful and, even if successful, such study and results may not be sufficient for regulatory applications, including emergency use or marketing applications, and that additional COVID-19 studies for opaganib are likely to be required by regulatory authorities to support such potential applications and the use or marketing of opaganib for COVID-19 patients, that opaganib will not be effective against emerging viral variants, as well as risks and uncertainties associated with (i) the initiation, timing, progress and results of the Company’s research, manufacturing, preclinical studies, clinical trials, and other therapeutic candidate development efforts, and the timing of the commercial launch of its commercial products and ones it may acquire or develop in the future; (ii) the Company’s ability to advance its therapeutic candidates into clinical trials or to successfully complete its preclinical studies or clinical trials (iii) the extent and number and type of additional studies that the Company may be required to conduct and the Company’s receipt of regulatory approvals for its therapeutic candidates, and the timing of other regulatory filings, approvals and feedback; (iv) the manufacturing, clinical development, commercialization, and market acceptance of the Company’s therapeutic candidates and Talicia®; (v) the Company’s ability to successfully commercialize and promote Movantik®, Talicia® and Aemcolo®; (vi) the Company’s ability to establish and maintain corporate collaborations; (vii) the Company’s ability to acquire products approved for marketing in the U.S. that achieve commercial success and build and sustain its own marketing and commercialization capabilities; (viii) the interpretation of the properties and characteristics of the Company’s therapeutic candidates and the results obtained with its therapeutic candidates in research, preclinical studies or clinical trials; (ix) the implementation of the Company’s business model, strategic plans for its business and therapeutic candidates; (x) the scope of protection the Company is able to establish and maintain for intellectual property rights covering its therapeutic candidates and commercial products and its ability to operate its business without infringing the intellectual property rights of others; (xi) parties from whom the Company licenses its intellectual property defaulting in their obligations to the Company; (xii) estimates of the Company’s expenses, future revenues, capital requirements and needs for additional financing; (xiii) the effect of patients suffering adverse events using investigative drugs under the Company’s Expanded Access Program; and (xiv) competition from other companies and technologies within the Company’s industry. More detailed information about the Company and the risk factors that may affect the realization of forward-looking statements is set forth in the Company’s filings with the Securities and Exchange Commission (SEC), including the Company’s Annual Report on Form 20-F filed with the SEC on March 18, 2021. All forward-looking statements included in this press release are made only as of the date of this press release. The Company assumes no obligation to update any written or oral forward-looking statement, whether as a result of new information, future events or otherwise unless required by law.

 

Company contact:

Adi Frish

Chief Corporate & Business Development Officer

RedHill Biopharma

+972-54-6543-112

adi@redhillbio.com

Media contacts:

U.S.: Bryan Gibbs, Finn Partners

+1 212 529 2236

bryan.gibbs@finnpartners.com

UK: Amber Fennell, Consilium

+44 (0) 7739 658 783  

fennell@consilium-comms.com

 

[1] Opaganib is an investigational new drug, not available for commercial distribution.

[2] Opaganib, an Oral Sphingosine Kinase-2 (SK2) Inhibitor in COVID-19 Pneumonia: A Randomized, Double-blind, Placebo-controlled Phase 2A Study, in Adult Subjects Hospitalized with SARS-CoV-2 Positive Pneumonia (NCT: 04414618). K. L. Winthrop, A. W. Skolnick, A. M. Rafiq, S. H. Beegle, J. Suszanski, G. Koehne, O.Barnett-Griness, A. Bibliowicz, R. Fathi, P. Anderson, G. Raday, G. Eagle, V. Katz Ben-Yair, H. S. Minkowitz, M. L. Levitt, M. S. Gordon

[3] Based on preliminary blinded blended data from 463 patients. The Company did not conduct a head-to-head comparison study in the same patient population. The theoretical comparison between the global Phase 2/3 study with opaganib and reported rates of mortality from large platform studies such as RECOVERY, and other studies in similar patient populations, serves as a general benchmark and should not be construed as a direct and/or applicable comparison as if the Company conducted a head-to-head comparison study.

[4] Xia C. et al. Transient inhibition of sphingosine kinases confers protection to influenza A virus infected mice. Antiviral Res. 2018 Oct; 158:171-177. Ebenezer DL et al. Pseudomonas aeruginosa stimulates nuclear sphingosine-1-phosphate generation and epigenetic regulation of lung inflammatory injury. Thorax. 2019 Jun;74(6):579-591.

[5] Full prescribing information for Movantik® (naloxegol) is available at: www.Movantik.com.  

[6] Full prescribing information for Talicia® (omeprazole magnesium, amoxicillin and rifabutin) is available at: www.Talicia.com.       

[7] Full prescribing information for Aemcolo® (rifamycin) is available at: www.Aemcolo.com.

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